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Enjoy a better life and brighter future through kidney disease treatment and research in San Antonio and South Texas

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MATTHIAS SIMON, M.D., PH.D.

Education

MD, St Bernward Hospital, Hildesheim, Germany 1994
PhD, Georg-August-University, Gottingen, Germany 1993

US Postgraduate training

Nephrology Fellowship: Dept of Medicine, Div. of Nephrology, UTHSC, San Antonio, Texas 2005-2006

Internal Medicine Residency: Dept. of Medicine, UTHSC, San Antonio, Texas 2003-2005

Nephrology Research Fellow: Dept. of Medicine, Div. of Nephrology, UTHSC, San Antonio, Texas 2000-2003

Postdoctoral Research Fellow: Div. of Nephrology: Dept. of Medicine, UTHSC, San Antonio, Texas 1995-1998

Foreign Postgraduate Training - Germany

Internal Medicine Residency: Dept of Medicine, Ludwig-Maximillian-University, Munich, Germany 1998-2000

Internal Medicine Residency: Dept of Medicine,  Georg-August-University, Gottingen, Germany 1994-1995

Pathology Residency: Institute of Pathology, Georg-August-University, Gottingen, Germany 1993-1994

Board Certifications

American Board of Internal Medicine - Internal Medicine
American Board of Internal Medicine - Nephrology

Professional Organizations, Societies

Bexar County Medical Society
Texas Medical Association

Awards and Fellowships

ACP Associates Program, 1 st Place Research Podium Competition 2004
UTHSC Research Day Winner 2004
Fellowship Grant of the National Kidney Foundation 1997
Fellowship Grant of the German Research Association 1995
FASEB Dupont Pharmaceuti cal Research Award 1991

Publications

Gröne H-J, Simon M, and Fuchs E: Autoradiographic characterization of angiotensin receptor subtypes in fetal and adult human kidney. Am J Physiol 262(2): F326-31, 1992

Fuchs E, Gröne H-J, Simon M, Laue A: Distribution of 125I-endothelin-1,-2,-3 binding sites in mammalian kidneys. Comp Biochem Physiol 101A: 775-78, 1992

Simon M , Gröne H-J, Jöhren O, Kullmer J, Plate KH, Risau W, and Fuchs E: Expression of vascular endothelial growth factor and its receptors in human renal ontogenesis and in adult kidney.  Am J Physiol 268(2):F240-50, 1995.

Gröne H-J, Simon M, and Gröne EF: Expression of vascular endothelial growth factor in renal vascular disease and renal allografts. J Pathology 177(3): 259-67, 1995.

Simon M , Röckl W, Hornig C, Gröne EF, Theis H, Weich HA, Fuchs E, Yayon A, Gröne HJ: Receptors of vascular endothelial growth factor/vascular permeability factor (VEGF/VPF) in fetal and adult human kidney: localization and [ 125I]VEGF binding sites. JASN 9(6): 1032-44, 1998.

Klanke B, Simon M, Röckl W, Weich HA, Stolte H, Gröne HJ: Effects of vascular endothelial growth factor (VEGF)/vascular permeability factor (VPF) on haemodynamics and permselectivity of the isolated perfused rat kidney. Nephrol Dial Transplant 13(4): 875-85, 1998.

Simon M , Cleary TG, Hernandez JD, Abboud HE: Shiga toxin 1 elicits diverse biologic responses in mesangial cells. Kidney Int. 54(4): 1117-27, 1998.

Simon M , Marish JG, Harris S, Hernandez JD, Olson M, Abboud HE: Expression of bone morphogenetic protein-7 (BMP-7) mRNA in the normal and ischemic adult rat kidney. Am J Physiol 276(45): F382-F389, 1999.

Ghosh-Choundhury G, Kim YS, Simon M, Wozney J, Harris S, Ghosh-Choundhury N, Abboud HE: Bone morphogenetic protein 2 inhibits platelet-derived growth factor-induced c-fos gene transcription and DNA synthesis in mesangial cells. Involvement of mitogen-activated protein kinase. J Biol Chem. 274(16): 10897-902, 1999.

Simon M , Feliers D, Arar M, Abboud HE: Cloning and characterization of the 5’-flanking region of murine bone morphogenetic protein-7 gene. Mol Cell Biochem  233(1-2): 31-37, 2002.

Quinibi WY, Hootkins RE, McDowell LL, Meyer, MS, Simon M, Garza RO, Pelham RW, Cleveland MV, Muenz LR, He DY, Nolan CR: Treatment of hyperphosphatemia in hemodialysis patients: The Calcium Acetate Renagel Evaluation (CARE Study). Kidney Int 65(5): 1914-26, 2004.

Xu Y-C, Simon M , Jin D-C, Barnes JL, Bhandari B, Zhang J-H, and Abboud HE: Mechanisms of mesangial cell apoptosis in immune complex glomerulonephritis. (in preparation)

Simon M , Zhang J-H, Tang Y, Bhandari B, Cleary T, and Abboud HE: Role of mitochondria and caspases in shiga toxin 1 induced apoptosis of human glomerular mesangial cells. (in preparation)

Clinic Locations

Northeast

11481 Toepperwein Road, Suite 1202
San Antonio, Texas 78233
210.655.8470

Seguin

711 E. Court Street
Seguin, Texas 78155
210.655.8470

New Braunfels

1561 IH 35 South
New Braunfels, Texas 78130
210.655.8470

Affiliated Hospitals

Compass Hospital

4743 Jones Maltsberger
San Antonio, TX 78247

Northeast Methodist

2412 Judson Road
San Antonio, TX 78233

Guadalupe Regional Medical Center - Seguin

1215 E. Court
Seguin, Texas  78155

Languages

English