Flavio Alvareze, MD

Clinic locations

11481 Toepperwein Road, Suite 1202
San Antonio, Texas

711 E. Court Street
Seguin, Texas 78155

New Braunfels
1561 IH 35 South
New Braunfels, Texas 78130

Affiliated Hospitals
Compass Hospital
4743 Jones Maltsberger
San Antonio, TX 78247

Northeast Baptist
8811 Village Drive
San Antonio, TX 78217-5440

Northeast Methodist
2412 Judson Road
San Antonio, TX 78233

Guadalupe Regional Medical Center
1215 E. Court
Seguin, Texas  78155


Matthias Simon, MD, PhD


MD, St Bernward Hospital, Hildesheim, Germany 1994
PhD, Georg-August-University, Gottingen, Germany 1993

US Postgraduate training

Nephrology Fellowship: Dept of Medicine, Div. of Nephrology, UTHSC, San Antonio, Texas 2005-2006
Internal Medicine Residency: Dept. of Medicine, UTHSC, San Antonio, Texas 2003-2005
Nephrology Research Fellow: Dept. of Medicine, Div. of Nephrology, UTHSC, San Antonio, Texas 2000-2003
Postdoctoral Research Fellow: Div. of Nephrology: Dept. of Medicine, UTHSC, San Antonio, Texas 1995-1998

Foreign Postgraduate Training - Germany

Internal Medicine Residency: Dept of Medicine, Ludwig-Maximillian-University, Munich, Germany 1998-2000
Internal Medicine Residency: Dept of Medicine,  Georg-August-University, Gottingen, Germany 1994-1995
Pathology Residency: Institute of Pathology, Georg-August-University, Gottingen, Germany 1993-1994

Board Certifications

American Board of Internal Medicine - Internal Medicine
American Board of Internal Medicine - Nephrology

Professional organizations, societies

Bexar County Medical Society
Texas Medical Association 

Awards and Fellowships

ACP Associates Program, 1 st Place Research Podium Competition 2004
UTHSC Research Day Winner 2004 
Fellowship Grant of the National Kidney Foundation 1997 
Fellowship Grant of the German Research Association 1995FASEB Dupont Pharmaceuti cal Research Award 1991


Gröne H-J, Simon M, and Fuchs E: Autoradiographic characterization of angiotensin receptor subtypes in fetal and adult human kidney. Am J Physiol 262(2): F326-31, 1992

Fuchs E, Gröne H-J, Simon M, Laue A: Distribution of 125I-endothelin-1,-2,-3 binding sites in mammalian kidneys. Comp Biochem Physiol 101A: 775-78, 1992
Simon M , Gröne H-J, Jöhren O, Kullmer J, Plate KH, Risau W, and Fuchs E: Expression of vascular endothelial growth factor and its receptors in human renal ontogenesis and in adult kidney.  Am J Physiol 268(2):F240-50, 1995.

Gröne H-J, Simon M, and Gröne EF: Expression of vascular endothelial growth factor in renal vascular disease and renal allografts. J Pathology 177(3): 259-67, 1995.

Simon M , Röckl W, Hornig C, Gröne EF, Theis H, Weich HA, Fuchs E, Yayon A, Gröne HJ: Receptors of vascular endothelial growth factor/vascular permeability factor (VEGF/VPF) in fetal and adult human kidney: localization and [ 125I]VEGF binding sites. JASN 9(6): 1032-44, 1998.

Klanke B, Simon M, Röckl W, Weich HA, Stolte H, Gröne HJ: Effects of vascular endothelial growth factor (VEGF)/vascular permeability factor (VPF) on haemodynamics and permselectivity of the isolated perfused rat kidney. Nephrol Dial Transplant 13(4): 875-85, 1998. 

Simon M , Cleary TG, Hernandez JD, Abboud HE: Shiga toxin 1 elicits diverse biologic responses in mesangial cells. Kidney Int. 54(4): 1117-27, 1998.

Simon M , Marish JG, Harris S, Hernandez JD, Olson M, Abboud HE: Expression of bone morphogenetic protein-7 (BMP-7) mRNA in the normal and ischemic adult rat kidney. Am J Physiol 276(45): F382-F389, 1999.

Ghosh-Choundhury G, Kim YS, Simon M, Wozney J, Harris S, Ghosh-Choundhury N, Abboud HE: Bone morphogenetic protein 2 inhibits platelet-derived growth factor-induced c-fos gene transcription and DNA synthesis in mesangial cells. Involvement of mitogen-activated protein kinase. J Biol Chem. 274(16): 10897-902, 1999.

Simon M , Feliers D, Arar M, Abboud HE: Cloning and characterization of the 5’-flanking region of murine bone morphogenetic protein-7 gene. Mol Cell Biochem  233(1-2): 31-37, 2002.

Quinibi WY, Hootkins RE, McDowell LL, Meyer, MS, Simon M, Garza RO, Pelham RW, Cleveland MV, Muenz LR, He DY, Nolan CR: Treatment of hyperphosphatemia in hemodialysis patients: The Calcium Acetate Renagel Evaluation (CARE Study). Kidney Int 65(5): 1914-26, 2004.

Xu Y-C, Simon M , Jin D-C, Barnes JL, Bhandari B, Zhang J-H, and Abboud HE: Mechanisms of mesangial cell apoptosis in immune complex glomerulonephritis. (in preparation)

Simon M , Zhang J-H, Tang Y, Bhandari B, Cleary T, and Abboud HE: Role of mitochondria and caspases in shiga toxin 1 induced apoptosis of human glomerular mesangial cells. (in preparation)

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